Assay Detail
Functional
CHEMBL833207
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Antiproliferative activity against PC-3 cancer cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Chemistry and biology of mercaptoacetamides as novel histone deacetylase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.26 | 4.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL178456 | — | — | 1 | 4.48 |
| CHEMBL178202 | — | — | 1 | 4.30 |
| CHEMBL181508 | — | — | 1 | 4.00 |
| CHEMBL180911 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL178456 | — | IC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL178202 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL181508 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL180911 | — | IC50 | = | 110000.0 | nM | - |