Assay Detail
Functional
CHEMBL833279
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration required to inhibit Coxsackie B3 virus induced cytopathicity in vero cells
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Coxsackievirus B3 |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antiviral evaluation of cis-substituted cyclohexenyl and cyclohexanyl nucleosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 5.23 | 5.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL343131 | — | — | 1 | 5.23 |
| CHEMBL195229 | — | — | 1 | - |
| CHEMBL371070 | — | — | 1 | - |
| CHEMBL195137 | — | — | 1 | - |
| CHEMBL194988 | — | — | 1 | - |
| CHEMBL372421 | — | — | 1 | - |
| CHEMBL373130 | — | — | 1 | - |
| CHEMBL192217 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL343131 | — | EC50 | = | 5840.0 | nM | 5.23 |
| CHEMBL195229 | — | EC50 | > | 200000.0 | nM | - |
| CHEMBL371070 | — | EC50 | > | 200000.0 | nM | - |
| CHEMBL195137 | — | EC50 | > | 200000.0 | nM | - |
| CHEMBL194988 | — | EC50 | = | 168000.0 | nM | - |
| CHEMBL372421 | — | EC50 | > | 200000.0 | nM | - |
| CHEMBL373130 | — | EC50 | > | 200000.0 | nM | - |
| CHEMBL192217 | — | EC50 | > | 200000.0 | nM | - |