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Assay Detail

CHEMBL833440

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Concentration of compound that inhibits 50% of growth of Compound was tested for its cytotoxicity by inhibiting the growth of
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Intermediate

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis of potent taxoids for tumor-specific delivery using monoclonal antibodies.
Miller ML, Roller EE, Wu X, Leece BA, Goldmacher VS, Chari RV, Ojima I.
Bioorg Med Chem Lett (2004) 14 : 4079 -4082
PubMed 15225730 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 10.00 10.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL185347 1 10.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL185347 IC50 = 0.1 nM 10.00