Assay Detail
Binding
CHEMBL833475
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In vitro inhibitory concentration against epithelial fatty acid binding protein(E-FABP)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.11 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL82293 | PALMITIC ACID | -1.0 | 1 | 5.92 |
| CHEMBL184795 | — | — | 1 | 5.52 |
| CHEMBL185595 | — | — | 1 | 5.17 |
| CHEMBL363032 | — | — | 1 | 5.04 |
| CHEMBL427320 | — | — | 1 | 4.85 |
| CHEMBL364141 | — | — | 1 | 4.77 |
| CHEMBL184817 | — | — | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL82293 | PALMITIC ACID | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL184795 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL185595 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL363032 | — | IC50 | = | 9100.0 | nM | 5.04 |
| CHEMBL427320 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL364141 | — | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL184817 | — | IC50 | = | 30000.0 | nM | 4.52 |