Assay Detail
Binding
CHEMBL833551
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Inhibitory concentration against alpha-galactosidase of coffee bean
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Coffea arabica |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Biological properties of D- and L-1-deoxyazasugars.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.86 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL110458 | MIGALASTAT | 4.0 | 1 | 8.52 |
| CHEMBL176021 | — | — | 1 | 4.89 |
| CHEMBL368121 | — | — | 1 | 4.17 |
| CHEMBL307429 | DUVOGLUSTAT | 2.0 | 1 | - |
| CHEMBL176206 | — | — | 1 | - |
| CHEMBL179130 | — | — | 1 | - |
| CHEMBL369046 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL110458 | MIGALASTAT | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL176021 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL368121 | — | IC50 | = | 67000.0 | nM | 4.17 |
| CHEMBL307429 | DUVOGLUSTAT | IC50 | = | 880000.0 | nM | - |
| CHEMBL176206 | — | IC50 | = | 260000.0 | nM | - |
| CHEMBL179130 | — | IC50 | = | 290000.0 | nM | - |
| CHEMBL369046 | — | IC50 | = | 160000.0 | nM | - |