Assay Detail
Functional
CHEMBL833579
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentrations at which 2-fold depression of extracellular virion DNA (HBV) was observed in 2.2.15 Cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepatitis B virus |
| Cell Type | HepG2 2.2.15 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
5'-Homoneplanocin A inhibits hepatitis B and hepatitis C.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.75 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL141 | LAMIVUDINE | 4.0 | 1 | 7.22 |
| CHEMBL310547 | — | — | 1 | 6.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL141 | LAMIVUDINE | EC50 | = | 60.0 | nM | 7.22 |
| CHEMBL310547 | — | EC50 | = | 530.0 | nM | 6.28 |