Assay Detail
Functional
CHEMBL833644
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Ability to inhibit [3H]SPD transport by L1210 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological evaluation of aminopolyamines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.14 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18794 | BIS(ETHYL)SPERMINE | — | 1 | 5.80 |
| CHEMBL364961 | — | — | 1 | 4.47 |
| CHEMBL306840 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18794 | BIS(ETHYL)SPERMINE | Ki | = | 1600.0 | nM | 5.80 |
| CHEMBL364961 | — | Ki | = | 33700.0 | nM | 4.47 |
| CHEMBL306840 | — | Ki | = | 285000.0 | nM | - |