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Assay Detail

CHEMBL833757

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Functional
Inhibitory concentration against Echovirus 9
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Viruses
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Design, synthesis, and antipicornavirus activity of 1-[5-(4-arylphenoxy)alkyl]-3-pyridin-4-ylimidazolidin-2-one derivatives.
Chang CS, Lin YT, Shih SR, Lee CC, Lee YC, Tai CL, Tseng SN, Chern JH.
J Med Chem (2005) 48 : 3522 -3535
PubMed 15887961 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 6.08 6.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL193014 1 6.55
CHEMBL195749 1 6.30
CHEMBL45426 1 5.88
CHEMBL194768 1 5.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL193014 IC50 = 280.0 nM 6.55
CHEMBL195749 IC50 = 500.0 nM 6.30
CHEMBL45426 IC50 = 1310.0 nM 5.88
CHEMBL194768 IC50 = 2630.0 nM 5.58