Assay Detail
Functional
CHEMBL833765
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Inhibitory concentration againstHuman Karpas 299 Anaplastic Large Cell Lymphoma (CD30+) at 4th hour; n=1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design, synthesis, and in vitro evaluation of dipeptide-based antibody minor groove binder conjugates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.43 | 9.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL179092 | — | — | 1 | 9.55 |
| CHEMBL117142 | — | — | 1 | 9.47 |
| CHEMBL105 | MITOMYCIN | 4.0 | 1 | 6.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL179092 | — | IC50 | = | 0.28 | nM | 9.55 |
| CHEMBL117142 | — | IC50 | = | 0.34 | nM | 9.47 |
| CHEMBL105 | MITOMYCIN | IC50 | = | 525.0 | nM | 6.28 |