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Assay Detail

CHEMBL833772

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration of the compound was determined against DNA synthesis in LN18 glioblastoma cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Glioblastoma
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Endothelin-converting enzyme-1 inhibition and growth of human glioblastoma cells.
Berger Y, Dehmlow H, Blum-Kaelin D, Kitas EA, Löffler BM, Aebi JD, Juillerat-Jeanneret L.
J Med Chem (2005) 48 : 483 -498
PubMed 15658862 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.72 4.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL194651 1 4.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL194651 IC50 = 19000.0 nM 4.72