Assay Detail

CHEMBL833825

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Functional

Concentration for inhibition of forskolin-stimulated cAMP accumulation in CCL39 cells

ChEMBL ↗

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Target

CHO-K1 (CHEMBL614031) ↗

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Primary target CHO-K1

CHEMBL614031

Anchored from Assay target.

Protein identity CHO-K1

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Cricetulus griseus
Cell Type	CHO-K1
Confidence	1 — Organism
Curated By	Intermediate

Target

CHO-K1 (CHEMBL614031) ↗

Type	CELL-LINE
Organism	Cricetulus griseus

Publication

Somatostatin receptor 1 selective analogues: 2. N(alpha)-Methylated scan.

Erchegyi J, Hoeger CA, Low W, Hoyer D, Waser B, Eltschinger V, Schaer JC, Cescato R, Reubi JC, Rivier JE.
J Med Chem (2005) 48 : 507 -514
PubMed 15658864 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	2	9.43	9.74

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL442494	—	—	2	9.74

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL442494	—	EC50	=	0.18	nM	9.74
CHEMBL442494	—	EC50	=	0.77	nM	9.11