Assay Detail
Functional
CHEMBL833836
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration against hepatitis B virus in Hep G2.2.15 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepatitis B virus |
| Cell Type | HepG2 2.2.15 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Application of phosphoramidate pronucleotide technology to abacavir leads to a significant enhancement of antiviral potency.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.26 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL192616 | — | — | 1 | 6.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL192616 | — | EC50 | = | 550.0 | nM | 6.26 |