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Assay Detail

CHEMBL833862

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory activity against growth of cultured A-549 cell line
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Expert

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

Induction of G2/M cell cycle arrest and apoptosis by a benz[f]indole-4,9-dione analog in cultured human lung (A549) cancer cells.
Lee EJ, Lee HJ, Park HJ, Min HY, Suh ME, Chung HJ, Lee SK.
Bioorg Med Chem Lett (2004) 14 : 5175 -5178
PubMed 15380222 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.20 6.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL187958 1 6.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL187958 IC50 = 630.0 nM 6.20