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Assay Detail

CHEMBL833924

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Functional
Cytotoxic concentration against HFF cells was determined
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HFF
Confidence 1 — Organism
Curated By Intermediate

Target

HFF (CHEMBL614071)
Type CELL-LINE
Organism Homo sapiens

Publication

Novel 4-amino-furo[2,3-d]pyrimidines as Tie-2 and VEGFR2 dual inhibitors.
Miyazaki Y, Matsunaga S, Tang J, Maeda Y, Nakano M, Philippe RJ, Shibahara M, Liu W, Sato H, Wang L, Nolte RT.
Bioorg Med Chem Lett (2005) 15 : 2203 -2207
PubMed 15837294 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.10 6.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL194911 1 6.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL194911 IC50 = 790.0 nM 6.10