Assay Detail
Functional
CHEMBL833932
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Potency towards AT 6.1 cell
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Potent and selective [2-imidazol-1-yl-2-(6-alkoxy-naphthalen-2-yl)-1-methyl-ethyl]-dimethyl-amines as retinoic acid metabolic blocking agents (RAMBAs).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.57 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL182438 | — | — | 1 | 6.60 |
| CHEMBL367357 | — | — | 1 | 6.60 |
| CHEMBL360771 | — | — | 1 | 6.52 |
| CHEMBL368448 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL182438 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL367357 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL360771 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL368448 | — | IC50 | < | 100.0 | nM | - |