Assay Detail
Functional
CHEMBL834001
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Inhibitory concentration against amyloid-beta aggregation
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-beta aggregation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.84 | 4.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL345124 | PROPIDIUM | — | 1 | 4.90 |
| CHEMBL179455 | — | — | 1 | 4.86 |
| CHEMBL361165 | — | — | 1 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL345124 | PROPIDIUM | IC50 | = | 12600.0 | nM | 4.90 |
| CHEMBL179455 | — | IC50 | = | 13800.0 | nM | 4.86 |
| CHEMBL361165 | — | IC50 | = | 17700.0 | nM | 4.75 |