Assay Detail
Functional
CHEMBL834005
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of mouse osteoblast-like 1.8 cells transformation into osteoclasts
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Nonpeptide alpha(v)beta3 antagonists: identification of potent, chain-shortened 7-oxo RGD mimetics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.72 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL179069 | — | — | 1 | 8.10 |
| CHEMBL181366 | — | — | 1 | 7.92 |
| CHEMBL369530 | — | — | 1 | 7.44 |
| CHEMBL180489 | — | — | 1 | 7.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL179069 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL181366 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL369530 | — | IC50 | = | 36.0 | nM | 7.44 |
| CHEMBL180489 | — | IC50 | = | 39.0 | nM | 7.41 |