Assay Detail
Functional
CHEMBL834087
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Effective concentrations at which 10-fold depression of intracellular intermediates of HBV DNA was observed in 2.2.15 Cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepatitis B virus |
| Cell Type | HepG2 2.2.15 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
5'-Homoneplanocin A inhibits hepatitis B and hepatitis C.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.93 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL141 | LAMIVUDINE | 4.0 | 1 | 6.64 |
| CHEMBL310547 | — | — | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL141 | LAMIVUDINE | EC50 | = | 230.0 | nM | 6.64 |
| CHEMBL310547 | — | EC50 | = | 6100.0 | nM | 5.21 |