Assay Detail
Functional
CHEMBL834441
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against LS174T (human colon carcinoma )cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LS174T |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Design, synthesis, and biological evaluation of achiral analogs of duocarmycin SA.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.93 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL183826 | — | — | 1 | 8.40 |
| CHEMBL183747 | — | — | 1 | 7.54 |
| CHEMBL427323 | — | — | 1 | 4.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL183826 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL183747 | — | IC50 | = | 29.0 | nM | 7.54 |
| CHEMBL427323 | — | IC50 | = | 13800.0 | nM | 4.86 |