Assay Detail
Functional
CHEMBL834623
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against human enterovirus EV71 (2231) genotype C
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Viruses |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and antipicornavirus activity of 1-[5-(4-arylphenoxy)alkyl]-3-pyridin-4-ylimidazolidin-2-one derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.55 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL193014 | — | — | 1 | 7.85 |
| CHEMBL195749 | — | — | 1 | 7.82 |
| CHEMBL194768 | — | — | 1 | 7.42 |
| CHEMBL45426 | — | — | 1 | 7.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL193014 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL195749 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL194768 | — | IC50 | = | 38.0 | nM | 7.42 |
| CHEMBL45426 | — | IC50 | = | 76.0 | nM | 7.12 |