Assay Detail
Functional
CHEMBL834706
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Inhibitory concentration against etoposide induced apoptosis in rat cortical neurons
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Novel pyrazinone mono-amides as potent and reversible caspase-3 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.14 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL179503 | — | — | 1 | 7.22 |
| CHEMBL366927 | — | — | 1 | 7.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL179503 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL366927 | — | IC50 | = | 90.0 | nM | 7.05 |