Assay Detail
Functional
CHEMBL835142
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition concentration required against triglyceride transfer of human Microsomal triglyceride transfer protein
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Microsomal triglyceride transfer protein large subunit (CHEMBL2569) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
5-Carboxamido-1,3,2-dioxaphosphorinanes, potent inhibitors of MTP.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.68 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL187696 | — | — | 1 | 6.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL187696 | — | IC50 | = | 210.0 | nM | 6.68 |