Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL835262

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity of compound towards dopamine receptor D1 was determined
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

The role of QSAR in dopamine interactions.
Hansch C, Verma RP, Kurup A, Mekapati SB.
Bioorg Med Chem Lett (2005) 15 : 2149 -2157
PubMed 15808487 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 9 7.18 8.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL426763 1 8.72
CHEMBL369367 1 8.47
CHEMBL177455 1 8.23
CHEMBL366679 1 8.11
CHEMBL367045 1 7.71
CHEMBL176169 1 7.15
CHEMBL367180 1 5.76
CHEMBL362060 1 5.37
CHEMBL367875 1 5.12

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL426763 Ki = 1.905 nM 8.72
CHEMBL369367 Ki = 3.388 nM 8.47
CHEMBL177455 Ki = 5.888 nM 8.23
CHEMBL366679 Ki = 7.762 nM 8.11
CHEMBL367045 Ki = 19.5 nM 7.71
CHEMBL176169 Ki = 70.79 nM 7.15
CHEMBL367180 Ki = 1737.8 nM 5.76
CHEMBL362060 Ki = 4265.8 nM 5.37
CHEMBL367875 Ki = 7585.78 nM 5.12