Assay Detail
Binding
CHEMBL835385
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Binding affinity towards human dopamine receptor D4 was determined
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
The role of QSAR in dopamine interactions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.41 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL108531 | — | — | 1 | 6.64 |
| CHEMBL109063 | — | — | 1 | 6.56 |
| CHEMBL109101 | — | — | 1 | 6.43 |
| CHEMBL110489 | — | — | 1 | 6.24 |
| CHEMBL108463 | — | — | 1 | 6.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL108531 | — | Ki | = | 229.09 | nM | 6.64 |
| CHEMBL109063 | — | Ki | = | 275.42 | nM | 6.56 |
| CHEMBL109101 | — | Ki | = | 371.54 | nM | 6.43 |
| CHEMBL110489 | — | Ki | = | 575.44 | nM | 6.24 |
| CHEMBL108463 | — | Ki | = | 676.08 | nM | 6.17 |