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Assay Detail

CHEMBL836174

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Equilibrium constant of compound for binding to the active sites in human PC-3 cell membranes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type PC-3
Confidence 1 — Organism
Curated By Intermediate

Target

PC-3 (CHEMBL390)
Type CELL-LINE
Organism Homo sapiens

Publication

Potent bombesin-like peptides for GRP-receptor targeting of tumors with 99mTc: a preclinical study.
Nock BA, Nikolopoulou A, Galanis A, Cordopatis P, Waser B, Reubi JC, Maina T.
J Med Chem (2005) 48 : 100 -110
PubMed 15634004 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 10.00 10.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL414307 1 10.15
CHEMBL266079 1 9.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL414307 Kd = 0.07 nM 10.15
CHEMBL266079 Kd = 0.14 nM 9.85