Assay Detail
Functional
CHEMBL837536
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Inhibitory concentration against growth of murine L1210 cells at 48 hours
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Polyamine-vectored iron chelators: the role of charge.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.09 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL150911 | — | — | 1 | 6.70 |
| CHEMBL192275 | — | — | 1 | 5.82 |
| CHEMBL194002 | — | — | 1 | 5.16 |
| CHEMBL432481 | DEFERITRIN | 2.0 | 1 | 4.72 |
| CHEMBL18794 | BIS(ETHYL)SPERMINE | — | 1 | 4.52 |
| CHEMBL427003 | — | — | 1 | 4.40 |
| CHEMBL70927 | DEFERIPRONE | 4.0 | 1 | 4.34 |
| CHEMBL191563 | — | — | 1 | - |
| CHEMBL191237 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL150911 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL192275 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL194002 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL432481 | DEFERITRIN | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL18794 | BIS(ETHYL)SPERMINE | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL427003 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL70927 | DEFERIPRONE | IC50 | = | 46000.0 | nM | 4.34 |
| CHEMBL191563 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL191237 | — | IC50 | > | 100000.0 | nM | - |