Assay Detail
Functional
CHEMBL837870
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration againstHuman Caki-1 Renal CellCarcinoma Cell Lines (CD70+) at 4th hour; n=1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CAKI-1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and in vitro evaluation of dipeptide-based antibody minor groove binder conjugates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.36 | 9.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL179092 | — | — | 1 | 9.26 |
| CHEMBL117142 | — | — | 1 | 9.23 |
| CHEMBL105 | MITOMYCIN | 4.0 | 1 | 6.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL179092 | — | IC50 | = | 0.55 | nM | 9.26 |
| CHEMBL117142 | — | IC50 | = | 0.59 | nM | 9.23 |
| CHEMBL105 | MITOMYCIN | IC50 | = | 251.0 | nM | 6.60 |