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Assay Detail

CHEMBL838105

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HIV protease
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Human immunodeficiency virus type 1 protease (CHEMBL243)
Type SINGLE PROTEIN
Organism Human immunodeficiency virus 1

Publication

Synthesis and antiviral activity of P1' arylsulfonamide azacyclic urea HIV protease inhibitors.
Huang PP, Randolph JT, Klein LL, Vasavanonda S, Dekhtyar T, Stoll VS, Kempf DJ.
Bioorg Med Chem Lett (2004) 14 : 4075 -4078
PubMed 15225729 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL130078 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL130078 EC50 = 10.0 nM 8.00