Assay Detail
Functional
CHEMBL838123
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration required for alpha-MSH stimulated cAMP production
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Cell line |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Piperazinebenzylamines as potent and selective antagonists of the human melanocortin-4 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.76 | 8.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL360716 | — | — | 1 | 8.42 |
| CHEMBL340355 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL360716 | — | EC50 | = | 3.8 | nM | 8.42 |
| CHEMBL340355 | — | EC50 | = | 80.0 | nM | 7.10 |