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Assay Detail

CHEMBL838617

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Binding
Inhibitory constant against human Carbonic anhydrase IX
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Carbonic anhydrase 9 (CHEMBL3594)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II.
Di Fiore A, De Simone G, Menchise V, Pedone C, Casini A, Scozzafava A, Supuran CT.
Bioorg Med Chem Lett (2005) 15 : 1937 -1942
PubMed 15780637 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.82 7.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL361827 1 7.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL361827 Ki = 15.0 nM 7.82