Assay Detail
Binding
CHEMBL838625
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity for rat serotonin 5-HT1A receptor using [3H]8-OH-DPAT as radioligand expressed in CHO cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | CHO |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Novel 3-aminochromans as potential pharmacological tools for the serotonin 5-HT(7) receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.59 | 7.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL367584 | — | — | 1 | 7.12 |
| CHEMBL182792 | — | — | 1 | 6.76 |
| CHEMBL95104 | — | — | 1 | 6.25 |
| CHEMBL183676 | — | — | 1 | 6.23 |
| CHEMBL2112053 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL367584 | — | Ki | = | 75.1 | nM | 7.12 |
| CHEMBL182792 | — | Ki | = | 174.0 | nM | 6.76 |
| CHEMBL95104 | — | Ki | = | 562.0 | nM | 6.25 |
| CHEMBL183676 | — | Ki | = | 594.0 | nM | 6.23 |
| CHEMBL2112053 | — | Ki | > | 1000.0 | nM | - |