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Assay Detail

CHEMBL838681

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Binding
Binding affinity of the [35S]- radiolabeled compound to dog Bradykinin receptor B1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Canis lupus familiaris
Confidence 9 — Direct single protein target
Curated By Expert

Target

B1 bradykinin receptor (CHEMBL4724)
Type SINGLE PROTEIN
Organism Canis lupus familiaris

Publication

Development of an efficient and selective radioligand for bradykinin B1 receptor occupancy studies.
Su DS, Markowitz MK, Murphy KL, Wan BL, Zrada MM, Harrell CM, O'Malley SS, Hess JF, Ransom RW, Chang RS, Wallace MA, Raab CE, Dean DC, Pettibone DJ, Freidinger RM, Bock MG.
Bioorg Med Chem Lett (2004) 14 : 6045 -6048
PubMed 15546726 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.30 9.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL359553 1 9.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL359553 Ki = 0.5 nM 9.30