Assay Detail
Binding
CHEMBL839527
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Binding affinity against 5-Hydroxy tryptamine 2C receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Aminotriazine 5-HT7 antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.50 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL180086 | — | — | 1 | 8.00 |
| CHEMBL413049 | — | — | 1 | 7.70 |
| CHEMBL182418 | — | — | 1 | 6.80 |
| CHEMBL182174 | — | — | 1 | - |
| CHEMBL182937 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL180086 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL413049 | — | Ki | = | 20.0 | nM | 7.70 |
| CHEMBL182418 | — | Ki | = | 160.0 | nM | 6.80 |
| CHEMBL182174 | — | Ki | > | 1000.0 | nM | - |
| CHEMBL182937 | — | Ki | > | 1000.0 | nM | - |