Assay Detail
Binding
CHEMBL839528
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity against 5-Hydroxy tryptamine 2C receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Diaminopyrimidine and diaminopyridine 5-HT7 ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.36 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL183423 | — | — | 1 | 7.89 |
| CHEMBL363452 | — | — | 1 | 7.82 |
| CHEMBL182071 | — | — | 1 | 7.40 |
| CHEMBL184789 | — | — | 1 | 6.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL183423 | — | Ki | = | 13.0 | nM | 7.89 |
| CHEMBL363452 | — | Ki | = | 15.0 | nM | 7.82 |
| CHEMBL182071 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL184789 | — | Ki | = | 476.0 | nM | 6.32 |