Assay Detail
Binding
CHEMBL839542
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards human Alpha-1 adrenergic receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
2-(Anilino)imidazolines and 2-(benzyl)imidazoline derivatives as h5-HT1D serotonin receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.04 | 7.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL276868 | — | — | 1 | 7.04 |
| CHEMBL312448 | XYLOMETAZOLINE | 3.0 | 1 | 7.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL276868 | — | Ki | = | 91.0 | nM | 7.04 |
| CHEMBL312448 | XYLOMETAZOLINE | Ki | = | 91.0 | nM | 7.04 |