Assay Detail
Binding
CHEMBL839579
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Binding affinity for human dopamine receptor D3
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Modeling the similarity and divergence of dopamine D2-like receptors and identification of validated ligand-receptor complexes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.37 | 9.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267930 | SPIPERONE | 2.0 | 1 | 9.60 |
| CHEMBL59725 | — | — | 1 | 9.30 |
| CHEMBL7927 | FAUC 113 | — | 1 | 5.30 |
| CHEMBL310843 | — | — | 1 | 5.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267930 | SPIPERONE | Ki | = | 0.25 | nM | 9.60 |
| CHEMBL59725 | — | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL7927 | FAUC 113 | Ki | = | 5000.0 | nM | 5.30 |
| CHEMBL310843 | — | Ki | = | 5300.0 | nM | 5.28 |