Assay Detail
Binding
CHEMBL839755
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Effective concentration against Nicotinic acetylcholine receptor alpha2-beta4 expressed in xenopus oocytes
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | Oocyte |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 4.45 | 4.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3 | NICOTINE | 4.0 | 1 | 4.68 |
| CHEMBL134752 | DIMETHYLPHENYLPIPERAZINIUM | — | 1 | 4.64 |
| CHEMBL497939 | CYTISINICLINE | 3.0 | 1 | 4.41 |
| CHEMBL667 | ACETYLCHOLINE | 4.0 | 1 | 4.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3 | NICOTINE | EC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL134752 | DIMETHYLPHENYLPIPERAZINIUM | EC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL497939 | CYTISINICLINE | EC50 | = | 39000.0 | nM | 4.41 |
| CHEMBL667 | ACETYLCHOLINE | EC50 | = | 83000.0 | nM | 4.08 |