Assay Detail
Binding
CHEMBL839758
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration against Nicotinic acetylcholine receptor alpha4-beta2 expressed in xenopus oocytes
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | Oocyte |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 5.19 | 5.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL497939 | CYTISINICLINE | 3.0 | 1 | 5.57 |
| CHEMBL3 | NICOTINE | 4.0 | 1 | 5.26 |
| CHEMBL134752 | DIMETHYLPHENYLPIPERAZINIUM | — | 1 | 4.75 |
| CHEMBL293975 | — | — | 1 | - |
| CHEMBL371808 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL497939 | CYTISINICLINE | EC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL3 | NICOTINE | EC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL134752 | DIMETHYLPHENYLPIPERAZINIUM | EC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL293975 | — | EC50 | > | 2000000.0 | nM | - |
| CHEMBL371808 | — | EC50 | > | 1000000.0 | nM | - |