Assay Detail
Functional
CHEMBL839979
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cAMP accumulation in human adenosine A3 receptor assay as inhibition of Cl-IB-MECA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.37 | 7.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL188035 | — | — | 1 | 7.47 |
| CHEMBL363150 | — | — | 1 | 7.38 |
| CHEMBL364319 | — | — | 1 | 7.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL188035 | — | Ki | = | 34.0 | nM | 7.47 |
| CHEMBL363150 | — | Ki | = | 42.0 | nM | 7.38 |
| CHEMBL364319 | — | Ki | = | 55.0 | nM | 7.26 |