Assay Detail
Binding
CHEMBL840052
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]AMPA binding to human Ionotropic glutamate receptor 2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Two prodrugs of potent and selective GluR5 kainate receptor antagonists actives in three animal models of pain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 5.66 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL14935 | TEZAMPANEL ANHYDROUS | 2.0 | 1 | 5.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL14935 | TEZAMPANEL ANHYDROUS | Ki | = | 2210.0 | nM | 5.66 |