Assay Detail
Binding
CHEMBL840149
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In vitro binding affinity for human 5-hydroxytryptamine 1B receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.16 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL101690 | — | — | 1 | 6.62 |
| CHEMBL361303 | — | — | 1 | 6.58 |
| CHEMBL361061 | — | — | 1 | 6.36 |
| CHEMBL184597 | — | — | 1 | 5.64 |
| CHEMBL365405 | — | — | 1 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL101690 | — | Ki | = | 240.0 | nM | 6.62 |
| CHEMBL361303 | — | Ki | = | 260.0 | nM | 6.58 |
| CHEMBL361061 | — | Ki | = | 440.0 | nM | 6.36 |
| CHEMBL184597 | — | Ki | = | 2300.0 | nM | 5.64 |
| CHEMBL365405 | — | Ki | = | 2400.0 | nM | 5.62 |