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Assay Detail

CHEMBL840820

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against hepatitis C virus; range 0.5-100 uM; (a)
22
Total Activities
22
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Hepacivirus hominis
Confidence 1 — Organism
Curated By Autocuration

Target

Hepatitis C virus (CHEMBL379)
Type ORGANISM
Organism Hepacivirus hominis

Publication

Synthesis of 2'-beta-C-methyl toyocamycin and sangivamycin analogues as potential HCV inhibitors.
Ding Y, An H, Hong Z, Girardet JL.
Bioorg Med Chem Lett (2005) 15 : 725 -727
PubMed 15664845 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 22 4.00 4.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL362765 1 4.00
CHEMBL609095 1 4.00
CHEMBL610570 1 4.00
CHEMBL364578 1 4.00
CHEMBL607683 1 4.00
CHEMBL610297 1 4.00
CHEMBL609666 1 4.00
CHEMBL609944 1 4.00
CHEMBL610309 1 4.00
CHEMBL610825 1 4.00
CHEMBL610818 1 4.00
CHEMBL610310 1 4.00
CHEMBL608803 1 4.00
CHEMBL608804 1 4.00
CHEMBL610317 1 4.00
CHEMBL607960 1 4.00
CHEMBL607961 1 4.00
CHEMBL610565 1 4.00
CHEMBL610571 1 4.00
CHEMBL610819 1 4.00
CHEMBL610312 1 4.00
CHEMBL609663 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL362765 EC50 = 100000.0 nM 4.00
CHEMBL609095 EC50 = 100000.0 nM 4.00
CHEMBL610570 EC50 = 100000.0 nM 4.00
CHEMBL364578 EC50 = 100000.0 nM 4.00
CHEMBL607683 EC50 = 100000.0 nM 4.00
CHEMBL610297 EC50 = 100000.0 nM 4.00
CHEMBL609666 EC50 = 100000.0 nM 4.00
CHEMBL609944 EC50 = 100000.0 nM 4.00
CHEMBL610309 EC50 = 100000.0 nM 4.00
CHEMBL610825 EC50 = 100000.0 nM 4.00
CHEMBL610818 EC50 = 100000.0 nM 4.00
CHEMBL610310 EC50 = 100000.0 nM 4.00
CHEMBL608803 EC50 = 100000.0 nM 4.00
CHEMBL608804 EC50 = 100000.0 nM 4.00
CHEMBL610317 EC50 = 100000.0 nM 4.00
CHEMBL607960 EC50 = 100000.0 nM 4.00
CHEMBL607961 EC50 = 100000.0 nM 4.00
CHEMBL610565 EC50 = 100000.0 nM 4.00
CHEMBL610571 EC50 = 100000.0 nM 4.00
CHEMBL610819 EC50 = 100000.0 nM 4.00
CHEMBL610312 EC50 = 100000.0 nM 4.00
CHEMBL609663 EC50 = 100000.0 nM 4.00