Assay Detail
Binding
CHEMBL841026
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Binding affinity for rat imidazoline receptor I-1 from crude P2 membranes
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Binding of an imidazopyridoindole at imidazoline I2 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.30 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL275970 | TRACIZOLINE | — | 1 | 8.00 |
| CHEMBL404505 | — | — | 1 | 7.16 |
| CHEMBL269236 | TRYPTOLINE | — | 1 | 6.75 |
| CHEMBL6310 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL275970 | TRACIZOLINE | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL404505 | — | Ki | = | 70.0 | nM | 7.16 |
| CHEMBL269236 | TRYPTOLINE | Ki | = | 180.0 | nM | 6.75 |
| CHEMBL6310 | — | Ki | > | 10000.0 | nM | - |