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Assay Detail

CHEMBL841608

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of human platelet aggregation collected with sodium citrate as anticoagulant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

Integrin alpha-IIb/beta-3 (CHEMBL2093869)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents.
Scarborough RM, Gretler DD.
J Med Chem (2000) 43 : 3453 -3473
PubMed 10999999 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.85 6.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1174 EPTIFIBATIDE 4.0 1 6.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1174 EPTIFIBATIDE IC50 = 140.0 nM 6.85