Assay Detail
Binding
CHEMBL841867
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Binding affinity towards Imidazoline I2 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Binding of beta-carbolines at 5-HT(2) serotonin receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.47 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL6310 | — | — | 1 | 7.92 |
| CHEMBL269538 | HARMINE | 1.0 | 1 | 7.66 |
| CHEMBL295234 | — | — | 1 | 6.83 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL6310 | — | Ki | = | 12.0 | nM | 7.92 |
| CHEMBL269538 | HARMINE | Ki | = | 22.0 | nM | 7.66 |
| CHEMBL295234 | — | Ki | = | 148.0 | nM | 6.83 |