Assay Detail
Binding
CHEMBL842090
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Inhibition of human sst5 receptor expressed in CHO cells
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Novel non-peptide ligands for the somatostatin sst3 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 13 | 6.18 | 9.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1823872 | SOMATOSTATIN | 3.0 | 1 | 9.85 |
| CHEMBL362859 | — | — | 1 | 6.16 |
| CHEMBL176313 | — | — | 1 | 5.95 |
| CHEMBL174490 | — | — | 1 | 5.92 |
| CHEMBL368334 | — | — | 1 | 5.79 |
| CHEMBL176730 | — | — | 1 | 5.73 |
| CHEMBL367699 | — | — | 1 | 5.67 |
| CHEMBL175197 | — | — | 1 | 5.65 |
| CHEMBL174872 | — | — | 1 | 5.63 |
| CHEMBL368176 | — | — | 1 | 5.44 |
| CHEMBL175356 | — | — | 1 | - |
| CHEMBL368993 | — | — | 1 | - |
| CHEMBL367716 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1823872 | SOMATOSTATIN | Ki | = | 0.14 | nM | 9.85 |
| CHEMBL362859 | — | Ki | = | 691.0 | nM | 6.16 |
| CHEMBL176313 | — | Ki | = | 1130.0 | nM | 5.95 |
| CHEMBL174490 | — | Ki | = | 1190.0 | nM | 5.92 |
| CHEMBL368334 | — | Ki | = | 1620.0 | nM | 5.79 |
| CHEMBL176730 | — | Ki | = | 1870.0 | nM | 5.73 |
| CHEMBL367699 | — | Ki | = | 2120.0 | nM | 5.67 |
| CHEMBL175197 | — | Ki | = | 2250.0 | nM | 5.65 |
| CHEMBL174872 | — | Ki | = | 2360.0 | nM | 5.63 |
| CHEMBL368176 | — | Ki | = | 3650.0 | nM | 5.44 |
| CHEMBL175356 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL368993 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL367716 | — | Ki | > | 10000.0 | nM | - |