Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL842153

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In Vitro cytotoxicity against human lung cancer cell line (A549)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Intermediate

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and biological evaluation of novel A-ring modified hexacyclic camptothecin analogues.
Kim DK, Ryu DH, Lee JY, Lee N, Kim YW, Kim JS, Chang K, Im GJ, Kim TK, Choi WS.
J Med Chem (2001) 44 : 1594 -1602
PubMed 11334569 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.29 6.29

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL41652 1 6.29

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL41652 IC50 = 507.0 nM 6.29