Assay Detail
Functional
CHEMBL842360
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of ET-1 stimulated vasoconstriction in rabbit femoral artery.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Oryctolagus cuniculus |
| Tissue | Femoral artery |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
1-benzyl-3-thioaryl-2-carboxyindoles as potent non-peptide endothelin antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL285368 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL285368 | — | Kd | = | 100.0 | nM | 7.00 |