Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL842749

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Predicted affinity for imidazoline receptor I2 by three field CoMFA model
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Nischarin (CHEMBL3923)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

2-(2-Phenylcyclopropyl)imidazolines: reversed enantioselective interaction at I(1) and I(2) imidazoline receptors.
Quaglia W, Bousquet P, Pigini M, Carotti A, Carrieri A, Dontenwill M, Gentili F, Giannella M, Maranca F, Piergentili A, Brasili L.
J Med Chem (1999) 42 : 2737 -2740
PubMed 10425083 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.60 6.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL94022 1 6.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL94022 Ki = 251.19 nM 6.60