Assay Detail
Functional
CHEMBL843253
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The compound was tested for the ability to inhibit inducible cell adhesion molecule expression (ICAM-1) in primary human endothelial cell line (HUVEC)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HUVEC |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and evaluation of aza HUN-7293.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.58 | 7.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2448561 | — | — | 1 | 7.58 |
| CHEMBL2448562 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2448561 | — | IC50 | = | 26.0 | nM | 7.58 |
| CHEMBL2448562 | — | IC50 | > | 3000.0 | nM | - |